Comparative Analysis among Six Proteins OCT4, SOX2, KLF4, C-MYC, NANOG, and LIN28 using Bio Info Tools

Abstract

Now, it is possible to treat various fatal diseases using iPSCs. Take damaged nerve tissue as an example; in that case, medical doctors might remove healthy skin cells from the patient. These skin cells are reprogrammed into the healthy nerve cell. The developed nerve cells would be transferred into the affected part of the body. This approach is helpful in the treatment and healing of diseases such as Parkinson’s disease.

Research is going on to find molecules that can either replace or catalyze the functionality of transcription factors and other regulators in iPS cell induction. While different aspects and other properties of stem cells are a mystery for researchers, reprogramming factors provide a new path for the research of therapeutic agents. With the exponential growth in the generation of iPSC in many ways, there is an urgent requirement for a cost-effective, animal-free alternative.

The analytical parameters of the reprogramming factors and the interaction studies are not well known. The question we raised here is whether any relationship exists between all the parameters and functionality of the selected transcription factors. So, this research paper is centralized on solving the given problem. Modern high-throughput molecular technologies can sorta set of gene products simultaneously. The present research paper used Bio Info Tools to discuss the detailed comparative analysis among six proteins “OCT4, SOX2, KLF4, C-MYC, NANOG, and LIN28”.