PSORIASIS DETECTION METHODOLOGY DISCUSSION AND COMPARISON TO DIFFERENT SKIN PARAMETERS

Abstract

Psoriasis is a common inflammatory skin disease characterized by abnormal keratinocyte inflammation and differentiation that has a major impact on patients’ quality and way-out of life. IL-36γ, a member of IL-36 cytokine family, is highly expressed in psoriasis and plays an important role in inflammation response and colour to cell differentiation. Several studies have linked psoriasis with metabolic syndrome (MS), but only a few of them have used population specific criteria for diagnosis of MS as observed reading the other papers. None of the previous studies have explored whether MS is more frequent in psoriasis when compared to another chronic inflammatory disease of skin or not. The concept of Sense of Coherence (SOC), the main concept in the theory of salutogenesis may help explain the substance of our growth as human being. There is a need of further investigation of Sense of Coherence (SOC), the central concept of salutogenesis and its relationship with long-term sickness such as psoriasis.